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STUDY: COVID-19 Jab Informed Consent Should Include Risk of ADE, May Worsen COVID-19 Disease


I stumbled upon this interesting study and felt obligated to share it with WLT readers.

Prominent scientists have warned about the risk of ADE (Antibody Dependent Enhancement) from mass vaccinations.

Recall Dr. Robert Malone’s warning of potentially reaching the worst case scenario of this experimental vaccination rollout.

Here’s his interview from Bannon’s War Room:

Given the waning protection of the COVID-19 jabs, the worst case scenario includes the virus replicating more efficiently than it would without a vaccine.

This scenario causes antibodies to enhance virus entry and replication in cells.

That’s ADE and a significant challenge to vaccine development.

Fraudci himself even had a rare moment of truth and talked about the risk of ADE in 2020.

If we’ve reached ADE, the only logical step is to shut down the COVID-19 jab campaign.

Dr. Malone’s interview was in July 2021, but it appears some researchers relayed the ADE concerns last year.

According to this study, informed consent to vaccine trial subjects must include the risk of ADE.

And the potential of the COVID-19 jabs worsening clinical disease.

The study was first published October 28, 2020 in the International Journal of Clinical Practice.

You can find a summary in the NIH Library.

However, a more detailed version is available in the Wiley Online Library.

Below are a few excerpts from the study.

I’ve highlighted extremely important points:

Methods used to conduct the study

Published literature was reviewed to identify preclinical and clinical evidence that COVID-19 vaccines could worsen disease upon exposure to challenge or circulating virus. Clinical trial protocols for COVID-19 vaccines were reviewed to determine if risks were properly disclosed.

Results of the study

COVID-19 vaccines designed to elicit neutralising antibodies may sensitise vaccine recipients to more severe disease than if they were not vaccinated. Vaccines for SARS, MERS and RSV have never been approved, and the data generated in the development and testing of these vaccines suggest a serious mechanistic concern: that vaccines designed empirically using the traditional approach (consisting of the unmodified or minimally modified coronavirus viral spike to elicit neutralising antibodies), be they composed of protein, viral vector, DNA or RNA and irrespective of delivery method, may worsen COVID-19 disease via antibody-dependent enhancement (ADE). This risk is sufficiently obscured in clinical trial protocols and consent forms for ongoing COVID-19 vaccine trials that adequate patient comprehension of this risk is unlikely to occur, obviating truly informed consent by subjects in these trials.


Medical ethics standards required that, given the extent of evidence in the medical literature reviewed above, the risk of ADE should be clearly and emphatically distinguished in the informed consent from risks observed rarely as well as the more obvious risk of lack of efficacy, which is unrelated to the specific risk of ADE. Based on the published literature, it should have been obvious to any skilled medical practitioner in 2019 that there is a significant risk to vaccine research subjects that they may experience severe disease once vaccinated, while they might only have experienced a mild, self-limited disease if not vaccinated. The consent should also clearly distinguish the specific risk of worsened COVID-19 disease from generic statements about risk of death and generic risk of lack of efficacy of the vaccine.


Given the strong evidence that ADE is a non-theoretical and compelling risk for COVID-19 vaccines and the “laundry list” nature of informed consents, disclosure of the specific risk of worsened COVID-19 disease from vaccination calls for a specific, separate, informed consent form and demonstration of patient comprehension in order to meet medical ethics standards. The informed consent process for ongoing COVID-19 vaccine trials does not appear to meet this standard. While the COVID-19 global health emergency justifies accelerated vaccine trials of candidates with known liabilities, such an acceleration is not inconsistent with additional attention paid to heightened informed consent procedures specific to COVID-19 vaccine risks.

If you know anyone who received the experimental COVID-19 jab, it’s worth showing them this study.

Ask them if they received informed consent about the risk of Antibody Dependent Enhancement.


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