Skip to main content
WeLoveTrump.com may receive compensation from affiliate partners for some links on the site. Read our full Disclosure here.

STUDY: Over 500 Genes with Altered Expression Post COVID-19 Jab


5,106 views

Remember when the fact-checkers said the experimental mRNA gene therapy couldn’t alter your DNA?

It was a ‘conspiracy theory!’

However, a study published in Current Issues in Molecular Biology presented evidence of “fast entry of BNT162b2 into the cells and subsequent intracellular reverse transcription of BNT162b2 mRNA into DNA.”

mRNA From Pfizer COVID-19 Jab Can be Reverse Transcribed into DNA, According to Study

Another shocking study presented evidence suggesting the clear possibility that in some people the shot causes significant changes in the gene expression of a massive number of genes, including some that are critical to immune system regulation.

Read the abstract from the study titled, “Four cases of cytokine storm after COVID-19 vaccination: Case report.”

The global coronavirus disease 2019 (COVID-19) pandemic has led to the rapid development of vaccines against this disease. Despite the success of the international vaccination program, adverse events following vaccination, and the mechanisms behind them, remain poorly understood. Here we present four cases of death following receipt of a second dose of COVID-19 vaccine, with no obvious cause identified at autopsy. Using RNA sequencing, we identified genes that were differentially expressed between our post-vaccination cases and a control group that died of blood loss and strangulation. Three hundred and ninety genes were found to be upregulated and 115 genes were downregulated in post-vaccination cases compared with controls. Importantly, genes involved in neutrophil degranulation and cytokine signaling were upregulated. Our results suggest that immune dysregulation occurred following vaccination. Careful observation and care may be necessary if an abnormally high fever exceeding 40°C occurs after vaccination, even with antipyretic drugs.

Here’s the full text version for the discussion and conclusions:

Discussion

Although COVID-19 infection has spread worldwide, protection through vaccination has been clearly effective in many countries. However, many drugs and vaccines have side effects, and. COVID-19 vaccines have been associated with several reports of adverse events including death (10–12). Thus, it is important to gather information about the risk of vaccination, although it can be difficult to identify the cause of death without clear data. While the causes of death of the cases reviewed in this study could not be identified by autopsy, RNA sequencing of blood samples obtained and properly stored shortly after death provided valuable information. RNA sequencing analysis using postmortem specimens has rarely been performed because of the degradation of RNA due to postmortem changes. However, in the present case group, it was possible to collect blood samples within 24 hours after death, which was relatively early, and RNA sequencing analysis may have been successful (13).

Although we have no way of knowing whether the cases we reported met these criteria, the RNA sequencing results suggested that an abnormal secretion of cytokines, possibly a cytokine storm, may have occurred after vaccination, resulting in SIRS and death. SIRS is defined as fulfilling at least two of the following criteria: fever >38.0°C or hypothermia <36.0°C, tachycardia >90 beats/minute, tachypnea >20 breaths/minute, leukocytosis >12×109/L or leucopoenia <4×109/L (14). SIRS is induced by various factors, such as infection, trauma, surgery, and ischemia. It has been reported that SIRS can occur due to COVID-19 infection (15). COVID-19 vaccination corresponds to pseudo-COVID-19 infection. Therefore, vaccination may induce SIRS. In the present four victims, it is assumed that the immune function was sensitized by the first vaccination and that the second vaccination made the patients more susceptible to developing SIRS. Meanwhile, it is possible that these victims had a constitutional predisposition to be more prone to develop SIRS due to vaccination. However, our results do not indicate what mainly caused this aberrant cytokine response. Further studies such as analysis of single nucleotide polymorphisms are needed. It is important to note that vaccination remains essential to prevent the spread of infection and should not be considered dangerous on the basis of these cases alone. Additional research is needed to identify risk factors responsible for severe adverse events associated with vaccination.

Conclusions

We present four cases of death following receipt of a second dose of COVID-19 vaccine, with no obvious cause identified at autopsy. RNA sequencing revealed that genes involved in neutrophil degranulation and cytokine signaling were upregulated in these cases, suggesting that immune dysregulation occurred following vaccination. Careful observation and care may be necessary if an abnormally high fever exceeding 40°C occurs after vaccination, even with antipyretic drugs.

Ashmedai breaks down the findings in Resisting the Intellectual Illiteratti:

Step #1: They found a total of 505 (yeah, that’s a lot) genes that were “differentially expressed [] between individuals with unknown cause of death (unknown group) and the control group”. 390 genes were ‘higher’/more expressed in the vaccine death patients, and 115 genes were ‘lower’/less expressed in the vaccine death patients, compared to the 2 control patients that died of other causes.

Step #2: They then had to identify these 505 RNA’s/genes – ie, what proteins were these coding for or relevant to.

Step #3: They then had to try and figure out what this combination of genes would do/cause. This is not the most exact science as there is a lot we still don’t understand about the human genome & proteins. They “estimated” that some of the genes expressed more in the vaccine death patients were involved in increasing immune cells and activity, such as cytokines (think of the dreaded covid “cytokine storm”, which is what they titled their study)3.

Step #3b: They extrapolated from the increased expression of these immune-system genes that there was aggressive immunological activity run amok – “these results provide evidence of a hyperactive immune response in the group with unknown cause of death” – that killed these patients – “the RNA sequencing results suggested that an abnormal secretion of cytokines, possibly a cytokine storm, may have occurred after vaccination, resulting in SIRS and death.”

(SIRS = Systemic Inflammatory Response Syndrome)

Limitations:

This is not necessarily an open-and-shut case. The authors stipulate that “However, in the present case group, it was possible to collect blood samples within 24 hours after death, which was relatively early, and RNA sequencing analysis may have been successful (13). Although we have no way of knowing whether the cases we reported met these criteria, the RNA sequencing results suggested that an abnormal secretion of cytokines, possibly a cytokine storm, may have occurred after vaccination, resulting in SIRS and death.”

This study furthermore is on a grand total of 6 subjects, of which only 4 were detectably vaccine injured, which is way too small to definitively extrapolate from here that this effect is occurring in vaccine injured patients on a grand scale, is caused by the vaccine on a grand scale, or that their interpretation of the RNA sequencing is correct.

However, in the broader context of everything else we know about these covid vaccines, this study is decidedly ominous and in a sane world would by itself be sufficient to halt the use of these vaccines at least until this epic danger signal was properly investigated and adjudicated.

Additional point:

A scientist in government employ whom I asked for his/her opinion on this thought that this study’s methodology was fairly poor. Firstly, there is a strong possibility that the RNA had substantially degraded by the time they extracted it from blood samples. Secondly, they did not get enough RNA samples from each patient. Thirdly, the analysis of the RNA itself was deficient (for reasons too technical to go into here). Fourthly, the correlation between detectable RNA in blood samples and protein expression often do not correlate so well.

To be clear, this does not mean that the study’s conclusions are therefore incorrect, just that the direct evidence is pretty weak – which means that follow up studies should be done with larger patient samples and more robust biomarker testing that can more reliably capture with better certainty changes in gene expression in vaccine injured people (or anything else too for that matter).



 

Join the conversation!

Please share your thoughts about this article below. We value your opinions, and would love to see you add to the discussion!

We Love Trump
Thanks for sharing!